Preferred Specimen(s) 1 mL serum
Transport Container No additive (red-top) or Plastic screw-cap vial
Transport Temperature Refrigerated 3 days
Reject Criteria
- Received frozen;
- Gross hemolysis
Methodology CLIA
Clinical Significance: The presence of IgG antibodies demonstrates prior infection with Cytomegalovirus (CMV). Seroconversion of CMV IgG from negative to positive or a significant rise in antibody level between paired sera is indicative of active or recent infection. Testing for IgM antibodies (also indicative of active or recent infection) is recommended to support a diagnosis of active disease.