Includes
ANCA Screen with Reflex to ANCA Titer, Myeloperoxidase Ab (MPO), Proteinase-3 Antibody
If ANCA Screen is positive, C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge.
Preferred Specimen(s): 2 mL serum
Minimum Volume: 0.8 mL
Transport Temperature: Room temperature
Specimen Stability
· Room temperature 7 days;
· Refrigerated: 14 days;
· Frozen 30 days
Reject Criteria:
· Gross hemolysis
· Hyperlipemic
· Icteric
Methodology: Immunoassay (IA)
Clinical Significance: Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.
| ANCA Screen | Neutrophil cytoplasmic Ab |
| P-ANCA Titer | Neutrophil cytoplasmic Ab.perinuclear |
| C-ANCA Titer | Neutrophil cytoplasmic Ab.classic |
| Atypical P-ANCA Titer | Neutrophil cytoplasmic Ab.perinuclear.atypical |
| Myeloperoxidase Ab | Myeloperoxidase Ab |
| Proteinase-3 Ab | Proteinase 3 Ab |