Preferred Specimen(s) 1 ml serum
Transport Container Plastic screw-cap vial
Transport Temperature
- Room temperature: Not defined,
- Refrigerated: Not defined,
- -20oC Long term
Methodology ELISA
Clinical Significance Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren’s syndrome.