Creatinine with Glomerular Filtration Rate, Estimated (eGFR)

Preferred Specimen(s) 1 mL serum

Transport Container Plastic screw-cap vial

Transport Temperature

  • Ambient 5 days,
  • Refrigerated 2 weeks

Reject Criteria

  • Hemolysis
  • Anticoagulants other than heparin

Methodology Spectrophotometry (SP)

Clinical Significance Serum creatinine is useful in the evaluation of kidney function and in monitoring renal dialysis. A serum creatinine result within the reference range does not rule out renal function impairment: serum creatinine is not sensitive to early renal damage since it varies with age, gender and ethnic background. The impact of these variables can be reduced by an estimation of the glomerular filtration rate using an equation that includes serum creatinine, age and gender.