Preferred Specimen(s) 1.0 mL serum
Instructions Separate serum from cells as soon as possible
Transport Temperature Refrigerated (cold packs)
Reject Criteria Received room temperature
Methodology ELISA
Clinical Significance Dengue hemorrhagic fever and Dengue shock syndrome are caused by infection of a RNA flavivirus transmitted by a mosquito vector. Paired acute and convalescent specimens that exhibit a significant change in titer are useful to confirm clinical diagnosis of infection.