Factor VIII Activity, Clotting

Preferred Specimen(s) 1.0 mL Citrate Plasma

Instruction Give detail of Oral Anticoagulant Therapy

Transport Container Plastic screw cap vial

Transport Temperature Frozen

Reject Criteria

  • Grossly hemolyzed,
  • lipemic specimens

Methodology Coagulation

Clinical Significance This test is useful to evaluate a prolonged aPTT. The most common form of hemophilia is caused by deficiency of factor VIII. Hemophilia A is an x-linked disorder affecting between 1 in 5,000 to 10,000 males.