Preferred Specimen(s) 1 mL serum collected in a (red-top) tube (no gel).
Transport Container Plastic screw-cap vial
Transport Temperature
- Refrigerated 3 days,
- -20oC Long term
Methodology ELISA
Clinical Significance: Hepatitis E virus (HEV) is the major etiologic agent of enterically transmitted non-A, non-B hepatitis worldwide and has a high case-fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti-HEV) are produced following infection. The titer of IgM anti-HEV declines rapidly during early convalescence; IgG anti-HEV persists and appears to provide at least short-term protection against disease.