Neuron Specific Enolase (NSE)

Preferred Specimen(s) 1 mL serum

Instructions NSE is high in platelets and RBC; therefore, plasma and hemolyzed specimens are not acceptable

Transport Container Plastic screw-cap vial

Transport Temperature Refrigerated (cold packs)

Reject Criteria

  • Plasma
  • Hemolysis

Methodology Enzyme Immunoassay

Clinical Significance This test is used to monitor disease progression and therapy in individuals with small cell lung cancer (SCLC) and in other cancers (e.g., prostate).