Preferred Specimen(s) 1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube
Transport Container Plastic screw-cap vial
Transport Temperature Frozen
Reject Criteria Received thawed
Methodology Immunoassay
Clinical Significance Increased activity is associated with increased risk of arterial thrombosis, such as with unexplained premature myocardial infarction. As an acute phase reactant, the activity is increased after an acute event. Studies suggest PAI-1 may be a prognostic marker in early stage breast cancer.