Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)

Preferred Specimen(s) 1 mL serum

Transport Container Plastic screw-cap vial

Transport Temperature Refrigerated (cold packs)

Methodology ELISA

Clinical Significance Tissue Transglutaminase Antibody, IgA, is useful in diagnosing gluten-sensitive enteropathies, such as Celiac Sprue Disease, and an associated skin condition, dermatitis herpetiformis. The IgG test is useful in patients who are IgA-deficient. The IgG test also provides support for gluten-sensitive enteropathies beyond IgA the test..